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Lung Cancer Research in the NCI-H358 Cell Line


Derived from the bronchioalveolar cancer of a human patient by A.F. Gazdar in 1981, the NCI-H358 cell line has served as a stable testing environment for lung cancer drug evaluations during preclinical trials. As an in vitro model for the testing of drugs, the NCI-H358 cell line can be transfected with optimal reagents to ensure the realistic nature of results pertaining to genetic mutations and resulting effects on cell proliferation. With a population doubling time of roughly 38 hours, the cell line is well-suited for preclinical research and drug testing that may lead to clinical trials.

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